Ms. JESSICA KEATING
 
 
First Name
JESSICA
Last Name
KEATING
University/Institution
Oregon Health and Science University
Email ID
keatinje@ohsu.edu
City
Portland
Country
United States
State
Oregon
Zip code
97202
Department
Neurology
Area of Research
Neurodegenerative disease
Area of Expertise
Parkinsons disease
Brief Description of Research Interest:
 

I am a third-year MD/PhD student/first-year graduate student studying Parkinson's Disease (PD) using a mouse model of idiopathic PD and a fly model of alpha-synuclein (the protein that characteristically aggregates in PD neurons) toxicity. I hope to approach disease pathogenesis from an aging and metabolism perspective by using metabolomic analysis in a PD mouse model to furnish targets for genetic or pharmacological manipulation in the fly and in mammalian cells. 

My past research experience also involves the circuits of pain and somatosensation in the mouse spinal cord, oxytocin receptor cells, post-stroke needs and care delivery for young stroke survivors (this research post also involved several opportunities for science communication), and cognition and memory in healthy aging. 

 
Representative Publications:
 

Gradwell MA, Ozeri-Engelhard N, Eisdorfer JT, Laflamme OD…Keating J…& Abraira VE. (2024). Multimodal sensory control of motor performance by glycinergic interneurons of the mouse spinal cord deep dorsal horn. Neuron 112, 1-26.

Bohic M, Upadhyay A, Eisdorfer JT, Keating J, Simon RC, Briones BA…& Abraira VE. (2023). A new Hoxb8FlpO mouse line for intersectional approaches to dissect developmentally defined adult sensorimotor circuits. Front Mol Neuro 16.

Keating J, Borschmann K, Johns H, Churilov L, & Bernhardt J. (2021). Shaping better care: Young stroke survivors’ preferred methods of meeting their unique needs. Neurology 96(13): e1701-10

Keating J, Affleck-Brodie C, Wiegand R, & Morcom AM. (2017). Aging, working memory capacity and the proactive control of recollection: An event-related potential study. PLoS ONE 12(7): e0180367