Dr. EMAN DESOKY
 
 
First Name
EMAN
Last Name
DESOKY
University/Institution
Vanderbilt University Medical Center
Email ID
eman.desoky@vumc.org
City
Nashville
Country
United States
State
Tennessee
Zip code
37203
Department
Area of Research
Clinical Pharmacy Pharmacology and Toxicology
Area of Expertise
Hepatology and Gastroenterology Metabolic syndrome
Brief Description of Research Interest:
 

I have been working in scientific research for more than ten years. I was concerned with chronic hepatic diseases such as liver fibrosis, non-alcoholic steatohepatitis (NASH), and liver cancer. I studied the effect of metabolic disorders such as insulin resistance as predisposing factors for NASH and liver cancer. As a Doctor of Clinical Pharmacy and pharmacology, I sought novel therapeutic interventions with a safety profile. I investigated different natural product effects on liver fibrosis, insulin resistance modulation, and NASH prevention. Also, I studied the pathophysiology of fibrosis, insulin resistance, and lipid metabolism looking for new biological molecules that have a fundamental role in disease prevention. Currently, I work in GCPR signaling in adipose tissue and its role in obesity and thermogenesis as well as the ANP clearance by NPRC receptors in obesity. 

 

 
Representative Publications:
 
  • E D Mohammed, R N El-Naga, R A Lotfy, A A Al- Gendy, E El-Demerdash, Anti-fibrotic potential of a Matthiola arabica isothiocyanates rich fraction: impact on oxidative stress, inflammatory and fibrosis markers,  2017, 72(10):614-624, Pharmazie.
  • Eman D. Mohammed, Zechuan Zhang, Wenfang Tian, Venkatanarayana Gangarapu, A. A. Al-Gendy, Jun Chen, Jifu Wei, Beicheng Sun, Modulation of IR as a therapeutic target to prevent NASH using NRF from Diceratella elliptica (DC.) jonsell. Strong Nrf2 and leptin inducer as well as NF-kB inhibitor, 2021, 80:153388, Phytomedicine
  • Eman D.  Mohammed, Ashraf B Abdel-Naim, Jin   Kangpeng , Runqiu   Jiang , Jifu Wei , Beicheng Sun, The mother relationship between insulin resistance and non-alcoholic steatohepatitis: Glucosinolates hydrolysis products as a promising insulin resistance-modulator and fatty liver-preventer,  2021, 264:118615 , Life Sci. - Eman D.  Mohammed, Ashraf B Abdel-Naim, Jin   Kangpeng , Runqiu   Jiang , Jifu Wei , Beicheng Sun, The mother relationship between insulin resistance and non-alcoholic steatohepatitis: Glucosinolates hydrolysis products as a promising insulin resistance-modulator and fatty liver-preventer,  2021, 264:118615 , Life Sci.